Ludger Custom Glycoprofiling Services
Ludger Custom Glycoprofiling Services
Ludger Custom Glycoprofiling Services
Ludger Structural Assignment
Ludger Method Validation


Glycan Analytical Services

Ludger's scientists have extensive experience in detailed glycan analysis and their expertise can be applied to both biologic drugs (biopharmaceuticals) and glycoconjugates relevant to medical research. The latter includes Medical Glycomics for Precision Medicine and we are involved in a number of pan-European collaborative R&D programmes in this field which are listed on the following page: www.ludger.com/research-and-development.

Our glycoanalytical support includes consultancy and custom glycoprofiling services as well as method development, validation and transfer. This flexible model enables our clients to get a quick start to expert glycoprofiling. For instance, intially you could outsource your glycoprofiling work to us, followed by the transfer of the optimised methods and technology into your laboratory

In drug development (innovator, biosimilar and biobetter drugs) the glycoprofiling information provided can be used for early stage development (e.g. clone selection), process optimisation (including production scale up), characterisation to support regulatory (e.g. IND) submissions, batch comparability studies and product lot release QC. This information will help address safety, efficacy, product consistency, stability, half-life, regulatory compliance, patent issues and comparability.

Examples of drugs we regularly work with are: Monoclonal antibodies, glycoprotein hormones (e.g. follicle stimulating hormone (FSH) and erythropoietin (EPO)) and virus vaccines. We can also analyse glycosphingolipids and heparin digests.





Detailed Characterisation of Biopharmaceutical Glycosylation

(Monosaccharide Analysis, Sialic Acid Analysis, Intact Released Glycan Analysis, Site Specific Glycan Analysis)




Method Validation





Method Transfer





High Throughput Analysis






Contacts

Initial Enquiries

Dr. Claire Morgan

Dr. Claire Morgan
Head of Business Development
claire.morgan@ludger.com

Glycoprofiling Services

Dr. Louise Royle

Dr. Louise Royle
Head of Glycoprofiling
louise.royle@ludger.com

High Throughput Analysis

Dr. Daniel Spencer

Dr. Daniel Spencer
Head of Development
daniel.spencer@ludger.com