Ludger Velocity Labelling Kit

Ludger Velocity Labelling Kit


LudgerTag™ 2AB and 2AA Glycan Labelling Kits with Safer Reductant Fluorescent

Fluorescent labelling methods for glycoprofiling of therapeutic glycoproteins are well established and aid subsequent separation and quantitation using a range of techniques. These include high performance liquid chromatography (HPLC and UHPLC), capillary electrophoresis (CE), and mass spectrometry.

Of the fluorescent labels available, 2-aminobenzamide (2-AB) and 2-aminobenzoic acid (2-AA) are most widely used for oligosaccharide profiling. Existing 2-AA and 2-AB labelling kits use sodium cyanoborohydride as a reducing agent during glycan labelling. This reagent is toxic so a fume cupboard should be used during handling. To conform with emerging Health and Safety regulations we are now replacing these with our new VP glycan kits that use picoline borane which is a significantly safer reductant. This technology, developed in collaboration with Leiden University Medical Centre, The Netherlands, has now been patented

The VP kits have the same glycan labelling performance as the traditional kits but are safer, more convenient (fewer vials to mix) and the reagents are more stable.


2-AB glycan labelling kit (2PB reductant)

2-AB glycan labelling kit (2PB reductant)

LT-KAB-VP24

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2-AB (2-aminobenzamide) is one of the most widely used fluorescent labels for glycosylation analysis. The LudgerTag 2-AB Labeling Kit includes all the reagents required to label up to 30 glycans samples.

procainamide glycan labelling kit (2PB reductant)

procainamide glycan labelling kit (2PB reductant)

LT-KPROC-VP24

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For labelling of free glycans with procainamide (PROC) 2- picoline borane reductant. Kit sufficient for 24 samples.

2-AB glycan labelling kit (2PB reductant)

2-AB glycan labelling kit (2PB reductant)

LT-KAB-VP96

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A new high throughput labelling kit for the labeling of free glycans with 2-aminobenzamide acid (2-AB). This kit contains 2-picoline borane as the reductant. Sufficient for 96 samples.

2-AA glycan labelling kit (2PB reductant)

2-AA glycan labelling kit (2PB reductant)

LT-KAA-VP24

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For labelling of free glycans with 2-aminobenzoic acid (2-AA). 2- picoline borane reductant. Kit sufficient for 24 samples.

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