N-Glycan - procainamide labelled

N-Glycan  - procainamide labelled


LudgerTag procainamide labeled glycans can be analyzed by UHPLC, HPLC, ESI-MS, and LC-ESI-MS methods. Because of its improved ionization efficiency compared to 2-AB labeling it can permit identification of minor glycans (<1% relative peak area) by ESI-MS.
Fluorescence response: Procainamide glycans show a much higher sensitivity as compared to 2-AB labeled glycans, providing peak heights three times higher than traditional 2-AB labeled glycans. The procainamide labeled sugars show comparable separation to HILIC-UHPLC assays with 2-AB.

Mass spectrometry response: Due to its high ionization efficiency, procainamide shows much higher sensitivities the seen with 2-AB. When analyzed using ESI-MS and ESI-MS/MS, procainamide produces twenty-two times higher peaks than 2-AB. This provides a great platform for the detection and identification on minor peaks by MS/MS analysis.

The labeled glycans are supplied as 20 pmols dried form from an aqueous solution. They are stable at least 5 years as supplied and after reconstitution.


Ludger N-Glycan Nomenclature Table

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N-Glycan Nomenclature Table


A1F glycan (FA2G2S1, G2FS1), procainamide labelled

CPROC-A1F-01

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Procainamide labeled fucosylated monosialo biantennary oligosaccharide

A3 glycan (A3G3S3), procainamide labelled

CPROC-A3-01

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Procainamide labeled triantennary oligosaccharide

FA2G1 glycan (G1F), procainamide labelled

CPROC-FA2G1-01

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Procainamide labeled fucosylated, asialo, monogalactosylated biantennary oligosaccharide

Man-5 glycan, procainamide labelled

CPROC-MAN5-01

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Procainamide labeled oligomannose oligosaccharide with 5 mannosyl residues

Man-6 glycan, procainamide labelled

CPROC-MAN6-01

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Procainamide labeled oligomannose oligosaccharide with 6 mannosyl residues

Man-7 glycan, procainamide labelled

CPROC-MAN7-01

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Procainamide labeled oligomannose oligosaccharide with 7 mannosyl residues

Man-8 glycan, procainamide labelled

CPROC-MAN8-01

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Procainamide labeled oligomannose oligosaccharide with 8 mannosyl residues

Man-9 glycan, procainamide labelled

CPROC-MAN9-01

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Procainamide labeled oligomannose oligosaccharide with 9 mannosyl residues

NA2 glycan (A2G2S1, G2S1), procainamide labelled

CPROC-NA2-01

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Procainamide labeled asialo, galactosylated biantennary oligosaccharide

NA3 glycan (A3G3), procainamide labelled

CPROC-NA3-01

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Procainamide labeled asialo, galactosylated triantennary oligosaccharide

NGA2 glycan (A2), procainamide labelled

CPROC-NGA2-01

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Procainamide labeled asialo, agalacto biantennary oligosaccharide

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