Glycan libraries

Glycan Libraries

Glycan libraries are made up of a mixture of species from a specific type of glycoprotein or as panels with common characteristics. Our glycan libraries have been used in pharmaceutical and biotech companies around the world. They meet our rigorous standards of quality and contain no salts or other additives that may interfere with advanced analytical techniques such as mass spectrometry which require the highest levels of purity.

The following is an example of glycan libraries produced from a specific glycoprotein: N-glycans released from human IgG antibody glycoprotein. This library contains fucosylated and bi-antennary glycans with variable sialylation.

O-Glycans released from fetuin glycoprotein (purified from fetal calf serum). This library contains mainly core 1 and core 2 O-glycans with variable sialylation.

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IgG N-glycan library (unlabelled)

CLIBN-IGG-01

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IgG N-glycan library, unlabelled, 25 μg

IgG N-glycan library (2-AB)

CAB-IGG-01

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IgG N-glycan library, 2AB labelled, 200pmol. (n.b. as this is already labelled it can be run directly on UHPLC) . A mixture of 2AB labelled fucosylated bi-antennary complex-type N-glycans (oligosaccharides) released from human IgG antibody glycoprotein.

IgG N-glycan library (APTS)

CAPTS-IGG-01

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IgG N-glycan library, APTS labelled, Amount: 10pmol.

IgG N-glycan library (procainamide)

CPROC-IGG-02

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IgG N-glycan library, Procainamide labelled, 50pmol.

IgG N-glycan (Permethylated)

CPM-C13-IGG-01*

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IgG N-glycan library, Permethylated with heavy (13C) methyl iodide, approx 20 MS runs.

IgG N-glycan (Permethylated)

CPM-IGG-01

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IgG N-glycan library, Permethylated, approx 20 MS runs.

Fetuin N-glycan library (unlabelled)

CLIBN-FETUIN-01

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Fetuin N-glycan library, approx 7.5 μg. A mixture of bi-, tri-, and tetra-antennary glycan standards with variable sialylation released from fetuin glycoprotein.